As an "old" hand & (worn out) experienced individual on this subject I have found what best works for me.
Key Word "what works for me"
A light snack 20- 30 minutes before taking meds usually works.
Now on some medications it gives you a warning about NOT eating grapefruit; Heed the warning! You Will get quite ill.

Right now my medication does not require food but I take it with dinner anyway - it can't hurt! But in the past it was a real problem especially when working or travelling. I used to take a medication which had to be refrigerated and I was travelling by car (6 times) across the U.S. But I try to be consistent and have it down to a science now. At my work, which is a school, I eat lunch with my colleagues and just nonchalantly take my pills and supplements. I really don't care what anyone might think. My energy and level of activity plus hard work defy the fact that anything is even wrong with me! That has been my formula!

Just take the pills, on time, with or without food - don't make life difficult for yourself just take the darned pills

I take my Juluca after my first few bites of dinner no matter what time I eat it. My care team says that it is good to stay close to the same time but a few hours one way of the other does not matter. Just my personal thoughts!

I take Biktarvy about an hour after eating so there’s still food in my stomach. If we’ve had an earlier dinner, I’ll have a pice if bread or something small